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Secretory Phenotype in Peripheral Blood Mononuclear Cells of Elderly Patients with Rheumatoid Arthritis.

Rejuvenation research - 1 Aug 2024

Wang Wenlong, Chen Yanjuan, Shen Yidi, Chen Jian, Yao Xiaoyang, Cheng Yongjun, Xu Jinzhong, Ma Lisha, Chen Yong, Zhang Chuanfu

Abstract excerpt

This study aims to investigate the expression differences of peripheral blood mononuclear cells (PBMCs) in patients with elderly rheumatoid arthritis (ERA). Differentially expressed genes (DEGs) of PBMCs between young patients with RA (RA_Y) and elderly patients with RA (RA_A) were identified by RNA sequencing using the DESeq2 package, followed by bioinformatics analysis. The overlapped targets of the current...

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PMID: 38814828
DOI: 10.1089/rej.2024.0008

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