Article
Evaluation of molecular residual disease in operable non-small cell lung cancer with gene fusions, MET exon skipping or de novo MET amplification.
Frontiers of medicine - 1 Aug 2024
Fu Rui, Xiong Yuanyuan, Cai Miao, Li Fang, Chen Rongrong, Wu Yilong, Zhong Wenzhao
Abstract excerpt
Gene fusions and MET alterations are rare and difficult to detect in plasma samples. The clinical detection efficacy of molecular residual disease (MRD) based on circulating tumor DNA (ctDNA) in patients with non-small cell lung cancer (NSCLC) with these mutations remains unknown. This prospective, non-intervention study recruited 49 patients with operable NSCLC with actionable gene fusions (ALK, ROS1, RET, and...
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