Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Risk and Resilience Variants in the Retinoic Acid Metabolic and Developmental Pathways Associated with Risk of FASD Outcomes.

Biomolecules - 10 May 2024

McKay Leo, Petrelli Berardino, Pind Molly, Reynolds James N, Wintle Richard F, Chudley Albert E, Drögemöller Britt, Fainsod Abraham, Scherer Stephen W, Hanlon-Dearman Ana, Hicks Geoffrey G

Abstract excerpt

Fetal Alcohol Spectrum Disorder (FASD) is a common neurodevelopmental disorder that affects an estimated 2-5% of North Americans. FASD is induced by prenatal alcohol exposure (PAE) during pregnancy and while there is a clear genetic contribution, few genetic factors are currently identified or understood. In this study, using a candidate gene approach, we performed a genetic variant analysis of retinoic acid (RA)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Exome Sequencing
Share to Fetal Alcohol Spectrum Disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to SHH gene

Share to SOX9 gene

Share to TBX1 gene

Share to Genetic Predisposition to Disease

Share to Pregnancy

Share to Tretinoin

Source

Open in PubMed Open full text

Identifiers

PMID: 38785976
DOI: 10.3390/biom14050569
PMCID: PMC11117505

Genes

SHH
SOX9
STRA6
TBX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Risk and Resilience Variants in the Retinoic Acid Metabolic and Developmental Pathways Associated with Risk of FASD Outcomes.PMID 38785976Read ↗

Fetal alcohol spectrum disorders: Genetic and epigenetic mechanismsSemantic proximity Read ↗

Genetic and epigenetic insights into fetal alcohol spectrum disordersSemantic proximity Read ↗

Review and gap analysis: molecular pathways leading to fetal alcohol spectrum disordersSemantic proximity Read ↗

Insights into retinoic acid deficiency and the induction of craniofacial malformations and microcephaly in fetal alcohol spectrum disorderSemantic proximity Read ↗

DNA Methylation Abundantly Associates with Fetal Alcohol Spectrum Disorder and its SubphenotypesSemantic proximity Read ↗

Analysis of alcohol-metabolizing enzymes genetic variants and RAR/RXR expression in patients diagnosed with fetal alcohol syndrome: a case-control study.Semantic proximity Read ↗

Fetal alcohol spectrum disorders and their transmission through genetic and epigenetic mechanismsSemantic proximity Read ↗

The Impact of Oxidative Stress on the Epigenetics of Fetal Alcohol Spectrum DisordersSemantic proximity Read ↗

The Impact of Oxidative Stress on the Epigenetics of Fetal Alcohol Spectrum DisordersSemantic proximity Read ↗

Alcohol-Induced Developmental Origins of Adult-Onset DiseasesSemantic proximity Read ↗

Genetic Influences on Fetal Alcohol Spectrum DisorderSemantic proximity Read ↗

Fetal Alcohol Spectrum Disorder (FASD) Associated Neural Defects: Complex Mechanisms and Potential Therapeutic TargetsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.