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Antigenic epitope analysis of Pakistani G3 and G9 rotavirus strains compared to vaccine strains revealed multiple amino acid differences.

Diagnostic microbiology and infectious disease - 1 Aug 2024

Sadiq Asma, Khan Tariq, Bostan Nazish, Yinda Claude Kwe, Matthijnssens Jelle

Abstract excerpt

Rotaviruses belong to genotype VP4-P[8] are a significant cause of severe loose diarrhea in infants and young children. In the present study, we characterised the complete genome of three of the Pakistani P[8]b RVA strains by Illumina HiSeq sequencing technology to determine the complete genotype constellation providing insight into the evolutionary dynamics of their genes using maximum likelihood analysis. The...

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PMID: 38759540
DOI: 10.1016/j.diagmicrobio.2024.116346

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