Article
Risk assessment of a highly pathogenic H5N1 influenza virus from mink.
Nature communications - 15 May 2024
Restori Katherine H, Septer Kayla M, Field Cassandra J, Patel Devanshi R, VanInsberghe David, Raghunathan Vedhika, Lowen Anice C, Sutton Troy C
Abstract excerpt
Outbreaks of highly pathogenic H5N1 clade 2.3.4.4b viruses in farmed mink and seals combined with isolated human infections suggest these viruses pose a pandemic threat. To assess this threat, using the ferret model, we show an H5N1 isolate derived from mink transmits by direct contact to 75% of exposed ferrets and, in airborne transmission studies, the virus transmits to 37.5% of contacts. Sequence analyses show...
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