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Article

Atypical familial hemophagocytic lymphohistiocytosis type 3 in children: A report of cases and literature review.

Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology - 1 May 2024

Zhao Qin, Zhao Qian, Tang Xuemei, An Yunfei, Zhang Zhiyong, Tomomasa Dan, Hijikata Atsushi, Yang Xi, Kanegane Hirokazu, Zhao Xiaodong

Abstract excerpt

BACKGROUND: Familial hemophagocytic lymphohistiocytosis type 3 (FHL3) is caused by UNC13D variants. The clinical manifestations of FHL3 are highly diverse and complex. Some patients exhibit atypical or incomplete phenotypes, making accurate diagnosis difficult. Our study aimed to broaden the understanding of the atypical FHL3 clinical spectrum. METHODS: In our study, we analyzed in detail the clinical features of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 38747707
DOI: 10.1111/pai.14136

Genes

FHL3
UNC13D

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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