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Article

Genetic polymorphisms affecting telomere length and their association with cardiovascular disease in the Heinz-Nixdorf-Recall study.

PloS one - 1 Jan 2024

Tannemann Nico, Erbel Raimund, Nöthen Markus M, Jöckel Karl-Heinz, Pechlivanis Sonali

Abstract excerpt

Short telomeres are associated with cardiovascular disease (CVD). We aimed to investigate, if genetically determined telomere-length effects CVD-risk in the Heinz-Nixdorf-Recall study (HNRS) population. We selected 14 single-nucleotide polymorphisms (SNPs) associated with telomere-length (p<10-8) from the literature and after exclusion 9 SNPs were included in the analyses. Additionally, a genetic risk score (GRS)...

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Identifiers

PMID: 38743757
DOI: 10.1371/journal.pone.0303357
PMCID: PMC11093374

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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