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Translational PET Imaging of Nectin-4 Expression in Multiple Different Cancers with 68 Ga-N188

1 May 2024

Abstract excerpt

Nectin cell adhesion molecule 4 (nectin-4) is a transmembrane protein overexpressed on a variety of cancers and plays an important role in oncogenic and metastatic processes. The nectin-4–targeted antibody–drug conjugate enfortumab vedotin has been approved for treating locally advanced or metastatic urothelial cancer, but the efficacy in other types of cancer remains to be explored. The aim of this study was to...

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PMID: 38719240
DOI: 10.2967/jnumed.123.266830

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