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Article

Association Between Neuroinflammation and Parkinson's Disease: A Comprehensive Mendelian Randomization Study.

Molecular neurobiology - 1 Dec 2024

Wang YiNi, Shi XinYu, Yin YaPing, Yang Fei, Zhang YiNan, He Xin, Wen Da, Li Bai-Xiang, Ma Kun

Abstract excerpt

The objective of the study is to determine the causal relationship and potential mechanisms between Parkinson's disease (PD) and neuroinflammatory and neurotoxic mediators. We conducted two-sample Mendelian randomization (2SMR) study and multivariable Mendelian randomization (MVMR) analysis to investigate the causality between PD and neuroinflammatory and neurotoxic mediators. The mediation analysis with MR was...

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PMID: 38709392
DOI: 10.1007/s12035-024-04197-2

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