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Article

The two autophagy-related proteins 8a and 8b play distinct physiological roles in Drosophila

1 May 2024

Abstract excerpt

Atg8 family proteins play crucial roles in autophagy to maintain cellular homeostasis. However, the physiological roles of Atg8 family proteins have not been systematically determined. In this study, we generated Atg8a and Atg8b (homologs of Atg8 in Drosophila melanogaster) knockout flies. We found that the loss of Atg8a affected autophagy and resulted in partial lethality, abnormal wings, decreased lifespan, and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 38701988
DOI: 10.1016/j.ygeno.2024.110853

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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