Estimating genomic relationships of metafounders across and within breeds using maximum likelihood, pseudo-expectation-maximization maximum likelihood and increase of relationships.

Abstract excerpt

BACKGROUND: The theory of "metafounders" proposes a unified framework for relationships across base populations within breeds (e.g. unknown parent groups), and base populations across breeds (crosses) together with a sensible compatibility with genomic relationships. Considering metafounders might be advantageous in pedigree best linear unbiased prediction (BLUP) or single-step genomic BLUP. Existing methods to...

Topics

• Animals
• Models, Genetic
• Likelihood Functions
• Pedigree
• Breeding
• Algorithms
• Sheep
• Genomics
• Computer Simulation
• Male
• Female