Article
The maternal vaginal microbiome partially mediates the effects of prenatal stress on offspring gut and hypothalamus.
Nature neuroscience - 1 Aug 2018
Jašarević Eldin, Howard Christopher D, Morrison Kathleen, Misic Ana, Weinkopff Tiffany, Scott Phillip, Hunter Christopher, Beiting Daniel, Bale Tracy L
Abstract excerpt
Early prenatal stress disrupts maternal-to-offspring microbiota transmission and has lasting effects on metabolism, physiology, cognition, and behavior in male mice. Here we show that transplantation of maternal vaginal microbiota from stressed dams into naive pups delivered by cesarean section had effects that partly resembled those seen in prenatally stressed males. However, transplantation of control maternal...
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