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Analysis of gene expression dynamics and differential expression in viral infections using generalized linear models and quasi-likelihood methods

9 Apr 2024

Abstract excerpt

Introduction: Our study undertakes a detailed exploration of gene expression dynamics within human lung organ tissue equivalents (OTEs) in response to Influenza A virus (IAV), Human metapneumovirus (MPV), and Parainfluenza virus type 3 (PIV3) infections. Through the analysis of RNA-Seq data from 19,671 genes, we aim to identify differentially expressed genes under various infection conditions, elucidating the...

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PMID: 38655085
DOI: 10.3389/fmicb.2024.1342328

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