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The future of cancer vaccines against colorectal cancer

2 Apr 2024

Abstract excerpt

INTRODUCTION: Colorectal cancer (CRC) is the second most lethal malignancy worldwide. Immune checkpoint inhibitors (ICIs) benefit only 15% of patients with mismatch repair-deficient/microsatellite instability (dMMR/MSI) CRC. The majority of patients are not suitable due to insufficient immune infiltration. Cancer vaccines are a potential approach for inducing tumor-specific immunity within the solid tumor...

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PMID: 38644655
DOI: 10.1080/14712598.2024.2341744

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