Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clinical difference on the variants and co-mutation in a Chinese cohort with ALK-positive advanced non-small cell lung cancer.

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico - 1 Oct 2024

Fu Ying, Liu Qing, Wang Xiaohan, Sun Liangchao, Han Xiao, Meng Xue

Abstract excerpt

PURPOSE: Despite the generally favourable prognoses observed in patients with ALK-positive non-small cell lung cancer (NSCLC), there remains significant variability in clinical outcomes. The objective of this study is to enhance patient stratification by examining both the specific sites of gene fusion and the presence of co-occurring mutations. METHODS: We collected retrospective clinical and pathological data...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anaplastic Lymphoma Kinase
Share to Carcinoma, Non-Small-Cell Lung

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to East Asian People

Share to Lung Neoplasms

Share to Oncogene Proteins, Fusion

Share to Progression-Free Survival

Share to Tumor Suppressor Protein p53

Source

Identifiers

PMID: 38637357
DOI: 10.1007/s12094-024-03481-w

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clinical difference on the variants and co-mutation in a Chinese cohort with ALK-positive advanced non-small cell lung cancer.PMID 38637357Read ↗

Therapeutic Advances of Rare ALK Fusions in Non-Small Cell Lung CancerSemantic proximity Read ↗

Mutation status analysis of 58 patients with advanced ALK fusion gene positive non small cell lung cancer.Semantic proximity Read ↗

Prevalence and clinicopathological characteristics of ALK fusion subtypes in lung adenocarcinomas from Chinese populations.Semantic proximity Read ↗

Molecular determinants of clinical outcomes for anaplastic lymphoma kinase-positive non-small cell lung cancer in Chinese patients: A retrospective study.Semantic proximity Read ↗

Mutation Status Analysis Of 58 Patients With Advanced ALK Fusion Gene Positive Non Small Cell Lung CancerSemantic proximity Read ↗

EML4‑ALK fusion gene in non‑small cell lung cancer (Review)Semantic proximity Read ↗

Clinicopathological characteristics of patients with non-small-cell lung cancer who harbor EML4-ALK fusion gene: a meta-analysis.Semantic proximity Read ↗

Unique molecular features and clinical outcomes in young patients with non-small cell lung cancer harboring ALK fusion genesSemantic proximity Read ↗

EML4-ALK fusion variant.3 and co-occurrent PIK3CA E542K mutation exhibiting primary resistance to three generations of ALK inhibitors.Semantic proximity Read ↗

The Genomic Characteristics of ALK Fusion Positive Tumors in Chinese NSCLC PatientsSemantic proximity Read ↗

The impact of the ALK fusion variant on clinical outcomes in EML4-ALK patients with NSCLC: a systematic review and meta-analysis.Semantic proximity Read ↗

EML4-ALK rearrangement and its clinical significance in Chinese patients with advanced non-small cell lung cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.