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Mutation status analysis of 58 patients with advanced ALK fusion gene positive non small cell lung cancer.

BMC pulmonary medicine - 1 Sept 2023

Yang Yuan, Lu Baohua, Hu Mingming, Wang Qunhui, Jiang Mei, Zhang Tongmei, Liu Zhe

Abstract excerpt

PURPOSE: To analyze the characteristics and prognostic values of Anaplastic Lymphoma Kinase (ALK) fusion gene partner, gene subtype and abundance in tumor tissues of advanced Non Small Cell Lung Cancer (NSCLC) patients with positive ALK fusion gene and to explore the best treatment mode of ALK-Tyrosine Kinase Inhibitors(TKIs). METHODS: Cases of advanced NSCLC patients with ALK positive confirmed by both Next...

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PMID: 37658352
DOI: 10.1186/s12890-023-02618-x
PMCID: PMC10472634

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