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Article

Central conducting lymphatic anomaly: from bench to bedside.

The Journal of clinical investigation - 15 Apr 2024

Garlisi Torales Luciana Daniela, Sempowski Benjamin A, Krikorian Georgia L, Woodis Kristina M, Paulissen Scott M, Smith Christopher L, Sheppard Sarah E

Abstract excerpt

Central conducting lymphatic anomaly (CCLA) is a complex lymphatic anomaly characterized by abnormalities of the central lymphatics and may present with nonimmune fetal hydrops, chylothorax, chylous ascites, or lymphedema. CCLA has historically been difficult to diagnose and treat; however, recent advances in imaging, such as dynamic contrast magnetic resonance lymphangiography, and in genomics, such as deep...

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PMID: 38618951
DOI: 10.1172/JCI172839
PMCID: PMC11014661

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