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Article

Body composition measures as a determinant of Alpelisib related toxicity.

Breast cancer research and treatment - 1 Jul 2024

Shachar Eliya, Raphael Ari, Katz Uriel, Kessner Rivka, Shachar Shlomit Strulov

Abstract excerpt

BACKGROUND: Body composition has emerged as an important prognostic factor in patients treated with cancer. Severe depletion of skeletal muscle, sarcopenia, has been associated with poor performance status and worse oncological outcomes. We studied patients with metastatic breast cancer receiving alpelisib, to determine if sarcopenia and additional body composition measures accounting for muscle and adiposity are...

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Identifiers

PMID: 38584192
DOI: 10.1007/s10549-024-07315-9
PMCID: PMC11182811

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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