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Identification of ferroptosis related genes and pathways in prostate cancer cells under erastin exposure

4 Apr 2024

Abstract excerpt

Abstract Background Few studies are focusing on the mechanism of erastin acts on prostate cancer (PCa) cells, and essential ferroptosis-related genes (FRGs) that can be PCa therapeutic targets are rarely known. Methods In this study, in vitro assays were performed and RNA-sequencing was used to measure the expression of differentially expressed genes (DEGs) in erastin-induced PCa cells. A series of bioinformatic...

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PMID: 38575966
DOI: 10.1186/s12894-024-01472-1

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