Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

LncRNA SNHG12 promotes cell proliferation and inhibits apoptosis of granulosa cells in polycystic ovarian syndrome by sponging miR-129 and miR-125b

2 Apr 2024

Abstract excerpt

BACKGROUND: Polycystic ovarian syndrome (PCOS) is the most common endocrine disease in women of childbearing age which is often associated with abnormal proliferation or apoptosis of granulosa cells (GCs). Studies proved that long non-coding RNA SNHG12 (lncRNA SNHG12) is significantly increased in ovarian cancer and cervical cancer patients and cells. The inhibition of lncRNA SNHG12 restrains the proliferation,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related molecular mechanisms research
Share to Lipid metabolism and disorders
Share to Ovarian function and disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38566229
DOI: 10.1186/s13048-024-01392-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

LncRNA SNHG12 promotes cell proliferation and inhibits apoptosis of granulosa cells in polycystic ovarian syndrome by sponging miR-129 and miR-125bPMID 38566229Read ↗

Downregulation of lncRNA ZFAS1 and upregulation of microRNA-129 repress endocrine disturbance, increase proliferation and inhibit apoptosis of ovarian granulosa cells in polycystic ovarian syndrome by downregulating HMGB1Semantic proximity Read ↗

Identification and potential value of candidate microRNAs in granulosa cells of polycystic ovary syndromeSemantic proximity Read ↗

miR-34a-5p modulation of polycystic ovary syndrome via targeting the NOTCH signaling pathwaySemantic proximity Read ↗

Long non-coding RNA H19 regulates proliferation of ovarian granulosa cells via STAT3 in polycystic ovarian syndromeSemantic proximity Read ↗

miR‑132 is upregulated in polycystic ovarian syndrome and inhibits granulosa cells viability by targeting Foxa1Semantic proximity Read ↗

Long Noncoding RNAs: Potential Regulators Involved in the Pathogenesis of Polycystic Ovary Syndrome.Semantic proximity Read ↗

Effects of Nesfatin-1 and Wnt /β-Catenin Pathway on OGCs in PCOSSemantic proximity Read ↗

The Role of microRNAs in Ovarian Granulosa Cells in Health and DiseaseSemantic proximity Read ↗

MiR-93-5p promotes granulosa cell apoptosis and ferroptosis by the NF-kB signaling pathway in polycystic ovary syndromeSemantic proximity Read ↗

Aberrant activation of the Hedgehog signaling pathway in granulosa cells from patients with polycystic ovary syndromeSemantic proximity Read ↗

Long noncoding RNA SNHG12 promotes the proliferation, migration, and invasion of trophoblast cells by regulating the epithelial–mesenchymal transition and cell cycleSemantic proximity Read ↗

Silencing circ_0058063 enhances proliferation and inhibits apoptosis in PCOS ovarian granulosa cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.