Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

AAV-delivered hepato-adrenal cooperativity in steroidogenesis: Implications for gene therapy for congenital adrenal hyperplasia

12 Mar 2024

Abstract excerpt

Despite the availability of life-saving corticosteroids for 70 years, treatment for adrenal insufficiency is not able to recapitulate physiological diurnal cortisol secretion and results in numerous complications. Gene therapy is an attractive possibility for monogenic adrenocortical disorders such as congenital adrenal hyperplasia; however, requires further development of gene transfer/editing technologies and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adrenal Hormones and Disorders
Share to Sexual Differentiation and Disorders
Share to Virus-based gene therapy research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38558568
DOI: 10.1016/j.omtm.2024.101232

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

AAV-delivered hepato-adrenal cooperativity in steroidogenesis: Implications for gene therapy for congenital adrenal hyperplasiaPMID 38558568Read ↗

Biology of the Adrenal Gland Cortex Obviates Effective Use of Adeno-Associated Virus Vectors to Treat Hereditary Adrenal Disorders.Semantic proximity Read ↗

Models of Congenital Adrenal Hyperplasia for Gene Therapies Testing.Semantic proximity Read ↗

Congenital adrenal hyperplasias.Semantic proximity Read ↗

Adeno-Associated Virus-Mediated Gene Therapy for Patients' Fibroblasts, Induced Pluripotent Stem Cells, and a Mouse Model of Congenital Adrenal Hyperplasia.Semantic proximity Read ↗

Congenital adrenal hyperplasia: from genetics and biochemistry to clinical practice, Part 1.Semantic proximity Read ↗

[Genetic adrenal diseases].Semantic proximity Read ↗

Diagnosis and management of congenital adrenal hyperplasia.Semantic proximity Read ↗

Congenital Adrenal Hyperplasia.Semantic proximity Read ↗

Evidence for a heterozygote advantage in congenital adrenal hyperplasia due to 21-hydroxylase deficiency.Semantic proximity Read ↗

Embryonic Development and Adult Regeneration of the Adrenal GlandSemantic proximity Read ↗

A Humanized and Viable Animal Model for Congenital Adrenal Hyperplasia-CYP21A2-R484Q Mutant Mouse.Semantic proximity Read ↗

Adrenal Cortex Development and Maintenance: Knowledge Acquired From Mouse ModelsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.