Article
Models of Congenital Adrenal Hyperplasia for Gene Therapies Testing.
International journal of molecular sciences - 10 Mar 2023
Glazova Olga, Bastrich Asya, Deviatkin Andrei, Onyanov Nikita, Kaziakhmedova Samira, Shevkova Liudmila, Sakr Nawar, Petrova Daria, Vorontsova Maria V, Volchkov Pavel
Abstract excerpt
The adrenal glands are important endocrine organs that play a major role in the stress response. Some adrenal glands abnormalities are treated with hormone replacement therapy, which does not address physiological requirements. Modern technologies make it possible to develop gene therapy drugs that can completely cure diseases caused by mutations in specific genes. Congenital adrenal hyperplasia (CAH) is an...
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