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Multiomics Analyses Provide New Insight into Genetic Variation of Reproductive Adaptability in Tibetan Sheep.

Molecular biology and evolution - 1 Mar 2024

Han Buying, Tian Dehong, Li Xue, Liu Sijia, Tian Fei, Liu Dehui, Wang Song, Zhao Kai

Abstract excerpt

Domestication and artificial selection during production-oriented breeding have greatly shaped the level of genomic variability in sheep. However, the genetic variation associated with increased reproduction remains elusive. Here, two groups of samples from consecutively monotocous and polytocous sheep were collected for genome-wide association, transcriptomic, proteomic, and metabolomic analyses to explore the...

Topics

Humans
Female
Sheep
Animals
Tibet
Genome-Wide Association Study
Multiomics
Proteomics
Reproduction
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38552245
DOI: 10.1093/molbev/msae058
PMCID: PMC10980521

Genes

BMPR1B
PAPPA

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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