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Mitophagy modulation for the treatment of cardiovascular diseases

26 Mar 2024

Abstract excerpt

BACKGROUND: Defects of mitophagy, the selective form of autophagy for mitochondria, are commonly observed in several cardiovascular diseases and represent the main cause of mitochondrial dysfunction. For this reason, mitophagy has emerged as a novel and potential therapeutic target. METHODS: In this review, we discuss current evidence about the biological significance of mitophagy in relevant preclinical models...

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Share to Autophagy in Disease and Therapy
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 38530070
DOI: 10.1111/eci.14199

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