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Anaerostipes hadrus , a butyrate-producing bacterium capable of metabolizing 5-fluorouracil

12 Mar 2024

Abstract excerpt

ABSTRACT Anaerostipes hadrus ( A. hadrus ) is a dominant species in the human gut microbiota and considered a beneficial bacterium for producing probiotic butyrate. However, recent studies have suggested that A. hadrus may negatively affect the host through synthesizing fatty acid and metabolizing the anticancer drug 5-fluorouracil, indicating that the impact of A. hadrus is complex and unclear. Therefore,...

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PMID: 38470044
DOI: 10.1128/msphere.00816-23

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