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Myelodysplasia-related gene mutations are associated with favorable prognosis in patients with TP53-mutant acute myeloid leukemia.

Annals of hematology - 1 Apr 2024

Chen Yi, Zheng Jing, Weng Yimei, Wu Zhengjun, Luo Xiaofeng, Qiu Yanyan, Lin Yanjuan, Hu Jianda, Wu Yong

Abstract excerpt

This study aimed to examine the characteristics and treatment outcomes of patients with TP53-mutant acute myeloid leukaemia (AML) and to explore potential prognostic factors. This retrospective analysis included 130 patients diagnosed with TP53-mutant AML at the Fujian Medical University Union Hospital between January 2016 and June 2023. Patients' ages ranged from 17 to 80 years, with a median age of 59 years....

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Adolescent
Aged
Aged, 80 and over
Leukemia, Myeloid, Acute
Myelodysplastic Syndromes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Tumor Suppressor Protein p53

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PMID: 38409598
DOI: 10.1007/s00277-024-05679-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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