Coexistence of blaNDM-5, blaCTX-M-15, blaOXA-232, blaSHV-182 genes in multidrug-resistant K. pneumoniae ST437-carrying OmpK36 and OmpK37 porin mutations: First report in Italy.

doi:10.1016/j.jgar.2024.02.015

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Article

Coexistence of blaNDM-5, blaCTX-M-15, blaOXA-232, blaSHV-182 genes in multidrug-resistant K. pneumoniae ST437-carrying OmpK36 and OmpK37 porin mutations: First report in Italy.

Journal of global antimicrobial resistance - 1 Jun 2024

Di Marcantonio Sascia, Perilli Mariagrazia, Alloggia Giovanni, Segatore Bernardetta, Miconi Gianfranca, Bruno Gianfranco, Frascaria Patrizia, Piccirilli Alessandra

Abstract excerpt

OBJECTIVES: K. pneumoniae is a common cause of severe hospital-acquired infections. In the present study, we have characterised the whole-genome of two K. pneumoniae ST437 belonging to the clonal complex CC258. METHODS: The whole-genome sequencing was performed by MiSeq Illumina, with a 2 × 300bp paired-end run. ResFinder 4.4.2 was used to detect acquired antimicrobial resistance genes (ARGs) and chromosomal...

Topics

Humans
Drug Resistance, Multiple, Bacterial
Klebsiella pneumoniae
Porins
Italy
beta-Lactamases
Whole Genome Sequencing
Bacterial Proteins
Anti-Bacterial Agents

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Klebsiella Infections

Microbial Sensitivity Tests

Virulence Factors

Genome, Bacterial

Multilocus Sequence Typing

Plasmids

Source

Open in PubMed

Identifiers

PMID: 38408564
DOI: 10.1016/j.jgar.2024.02.015

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