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Clinical use of progesterone in human sperm preparation media for increasing IVF success

20 Oct 2023

Abstract excerpt

RESEARCH QUESTION: Can the addition of progesterone and neurotensin, molecular agents found in the female reproductive tract, after sperm washing increase the fertilization potential of human spermatozoa? DESIGN: (i) Cohort study of 24 men. Spermatozoa selected by swim-up were incubated in either progesterone or neurotensin (0.1-100 µM) for 1-4 h, and hyperactive motility and binding to hyaluronan (0.1-100 µM)...

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PMID: 38402675
DOI: 10.1016/j.rbmo.2023.103625

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