Article
Characterizing genetic transmission networks among newly diagnosed HIV-1 infected individuals in eastern China: 2012-2016.
PloS one - 1 Jan 2022
Ding Xiaobei, Chaillon Antoine, Pan Xiaohong, Zhang Jiafeng, Zhong Ping, He Lin, Chen Wanjun, Fan Qin, Jiang Jun, Luo Mingyu, Xia Yan, Guo Zhihong, Smith Davey M
Abstract excerpt
We aimed to elucidate the characteristics of HIV molecular epidemiology and identify transmission hubs in eastern China using genetic transmission network and lineage analyses. HIV-TRACE was used to infer putative relationships. Across the range of epidemiologically-plausible genetic distance (GD) thresholds (0.1-2.0%), a sensitivity analysis was performed to determine the optimal threshold, generating the...
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