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Global spread of the linezolid-resistant Enterococcus faecalis ST476 clonal lineage carrying optrA

15 Feb 2024

Abstract excerpt

OBJECTIVES: To investigate the global distribution of an optrA-harbouring linezolid-resistant Enterococcus faecalis ST476 clonal lineage. METHODS: Comprehensive searches of the NCBI database were performed to identify published peer-reviewed articles and genomes of E. faecalis ST476. Each genome was analysed for resistome, virulome, OptrA variant and optrA genetic contexts. A phylogenetic comparison of ST476...

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PMID: 38366373
DOI: 10.1093/jac/dkae039

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