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Article

Interplay of polygenic liability with birth-related, somatic, and psychosocial factors in anorexia nervosa risk: a nationwide study.

Psychological medicine - 1 Jul 2024

Papini Natalie M, Presseller Emily, Bulik Cynthia M, Holde Katrine, Larsen Janne T, Thornton Laura M, Albiñana Clara, Vilhjálmsson Bjarni J, Mortensen Preben B, Yilmaz Zeynep, Petersen Liselotte V

Abstract excerpt

BACKGROUND: Although several types of risk factors for anorexia nervosa (AN) have been identified, including birth-related factors, somatic, and psychosocial risk factors, their interplay with genetic susceptibility remains unclear. Genetic and epidemiological interplay in AN risk were examined using data from Danish nationwide registers. AN polygenic risk score (PRS) and risk factor associations, confounding...

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PMID: 38347808
DOI: 10.1017/S0033291724000175
PMCID: PMC11323254

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