Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Itraconazole inhibits tumor growth via CEBPB ‐mediated glycolysis in colorectal cancer

26 Jan 2024

Abstract excerpt

Advanced colorectal cancer (CRC) is characterized by a high recurrence and metastasis rate, which is the primary cause of patient mortality. Unfortunately, effective anti-cancer drugs for CRC are still lacking in clinical practice. We screened FDA-approved drugs by utilizing targeted organoid sequencing data and found that the antifungal drug itraconazole had a potential therapeutic effect on CRC tumors. However,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Cancer Genomics and Diagnostics
Share to Colorectal Cancer Treatments and Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38278779
DOI: 10.1111/cas.16082

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Itraconazole inhibits tumor growth via CEBPB ‐mediated glycolysis in colorectal cancerPMID 38278779Read ↗

ENO3 promotes colorectal cancer progression by enhancing cell glycolysisSemantic proximity Read ↗

Identification of Metabolic-Associated Genes for the Prediction of Colon and Rectal AdenocarcinomaSemantic proximity Read ↗

Survival-associated Metabolic Genes in Colon and Rectal CancersSemantic proximity Read ↗

ABCE1 facilitates tumour progression via aerobic glycolysis and inhibits cell death in human colorectal cancer cells through the p53 signalling pathwaySemantic proximity Read ↗

Cell Glycolysis Related Gene Signature Predicts Survival of Patients with Colorectal CancerSemantic proximity Read ↗

ALDOC and PGK1 coordinately induce glucose metabolism reprogramming and promote development of colorectal cancerSemantic proximity Read ↗

Identification and validation of a novel LncRNA TRG-AS1 that inhibits colorectal cancer proliferation and glycolysisSemantic proximity Read ↗

Characterization of butyrate-metabolism in colorectal cancer to guide clinical treatmentSemantic proximity Read ↗

MDFI promotes the proliferation and tolerance to chemotherapy of colorectal cancer cells by binding ITGB4/LAMB3 to activate the AKT signaling pathwaySemantic proximity Read ↗

Glycolysis Changes the Microenvironment and Therapeutic Response Under the Driver of Gene Mutation in Esophageal AdenocarcinomaSemantic proximity Read ↗

miR-500a-3p/CDK6 Axis Suppresses Aerobic Glycolysis in Colorectal CancerSemantic proximity Read ↗

Glycerophosphodiester phosphodiesterase 1 (GDE1) acts as a potential tumor suppressor and is a novel therapeutic target for non-mucin-producing colon adenocarcinomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.