Article
Genome-wide equine preimplantation genetic testing enabled by simultaneous haplotyping and copy number detection.
Scientific reports - 23 Jan 2024
De Coster T, Zhao Y, Tšuiko O, Demyda-Peyrás S, Van Soom A, Vermeesch J R, Smits K
Abstract excerpt
In different species, embryonic aneuploidies and genome-wide errors are a major cause of developmental failure. The increasing number of equine embryos being produced worldwide provides the opportunity to characterize and rank or select embryos based on their genetic profile prior to transfer. Here, we explored the possibility of generic, genome-wide preimplantation genetic testing concurrently for aneuploidies...
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