Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Variant of the lactase LCT gene explains association between milk intake and incident type 2 diabetes.

Nature metabolism - 1 Jan 2024

Luo Kai, Chen Guo-Chong, Zhang Yanbo, Moon Jee-Young, Xing Jiaqian, Peters Brandilyn A, Usyk Mykhaylo, Wang Zheng, Hu Gang, Li Jun, Selvin Elizabeth, Rebholz Casey M, Wang Tao, Isasi Carmen R, Yu Bing, Knight Rob, Boerwinkle Eric, Burk Robert D, Kaplan Robert C, Qi Qibin

Abstract excerpt

Cow's milk is frequently included in the human diet, but the relationship between milk intake and type 2 diabetes (T2D) remains controversial. Here, using data from the Hispanic Community Health Study/Study of Latinos, we show that in both sexes, higher milk intake is associated with lower risk of T2D in lactase non-persistent (LNP) individuals (determined by a variant of the lactase LCT gene, single nucleotide...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cattle
Share to Diabetes Mellitus, Type 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genotype

Share to Lactase

Source

Open in PubMed Open full text

Identifiers

PMID: 38253929
DOI: 10.1038/s42255-023-00961-1
PMCID: PMC11097298

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Variant of the lactase LCT gene explains association between milk intake and incident type 2 diabetes.PMID 38253929Read ↗

Large-scale searching for causal relationships of milk consumption with multi-omics and disease susceptibility: A phenome-wide Mendelian randomization study.Semantic proximity Read ↗

Cow’s Milk: A Benefit for Human Health? Omics Tools and Precision Nutrition for Lactose Intolerance ManagementSemantic proximity Read ↗

Higher milk consumption is associated with a lower risk of diabetes mellitus: A case-control study.Semantic proximity Read ↗

Association of Estimated Daily Lactose Consumption, Lactase Persistence Genotype (rs4988235), and Gut Microbiota in Healthy Adults in the United States.Semantic proximity Read ↗

Gut-microbiome-related LCT genotype and 2-year changes in body composition and fat distribution: the POUNDS Lost Trial.Semantic proximity Read ↗

Human milk variation is shaped by maternal genetics and impacts the infant gut microbiomeSemantic proximity Read ↗

Associations between lactase persistence and the metabolic syndrome in a cross-sectional study in the Canary Islands.Semantic proximity Read ↗

Large-scale association analyses identify host factors influencing human gut microbiome compositionSemantic proximity Read ↗

Strain-level analysis of <i>Bifidobacterium spp</i> . from gut microbiomes of adults of differing lactase persistence genotypesSemantic proximity Read ↗

Milk intake, lactase persistence genotype, plasma proteins and risks of cardiovascular events in the Swedish general population.Semantic proximity Read ↗

Evidence for a causal association between milk intake and cardiometabolic disease outcomes using a two-sample Mendelian Randomization analysis in up to 1,904,220 individualsSemantic proximity Read ↗

Ileal Lactase Expression Associates with Lactase Persistence Genotypes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.