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Prognostic Impact of TP53 Mutations in Metastatic Nonsquamous Non-small-cell Lung Cancer.

Clinical lung cancer - 1 May 2024

Mathiot Laurent, Nigen Benoit, Goronflot Thomas, Hiret Sandrine, Doucet Ludovic, Pons-Tostivint Elvire, Bennouna Jaafar, Denis Marc G, Herbreteau Guillaume, Raimbourg Judith

Abstract excerpt

BACKGROUND: The prognostic impact of TP53 mutations in advanced or metastatic nonsquamous non-small-cell lung cancer (nsNSCLC) patients treated with chemotherapy and/or immune checkpoint inhibitors (ICI) remains unclear. MATERIALS AND METHODS: We retrospectively collected data from patients with nsNSCLC treated in the first line from January 2018 to May 2021. The patient was separated into 2 groups according to...

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Aged, 80 and over
Antineoplastic Combined Chemotherapy Protocols
Carcinoma, Non-Small-Cell Lung
Immune Checkpoint Inhibitors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Tumor Suppressor Protein p53

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PMID: 38218680
DOI: 10.1016/j.cllc.2023.12.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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