Article
Glycolysis Induced by METTL14 Is Essential for Macrophage Phagocytosis and Phenotype in Cervical Cancer.
Journal of immunology (Baltimore, Md. : 1950) - 15 Feb 2024
Wang Bingyu, Mao Zhonghao, Ye Jinwen, Jiao Xinlin, Zhang Teng, Wang Qi, Han Sai, Zhang Youzhong, Wang Chunling, Dong Taotao, Cui Baoxia
Abstract excerpt
N 6-methyladenosine (m6A) is the most abundant mRNA modification in mammals and it plays a vital role in various biological processes. However, the roles of m6A on cervical cancer tumorigenesis, especially macrophages infiltrated in the tumor microenvironment of cervical cancer, are still unclear. We analyzed the abnormal m6A methylation in cervical cancer, using CaSki and THP-1 cell lines, that might influence...
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