Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effects of different alkylating agents on photoreceptor degeneration and proliferative response of Müller glia

2 Jan 2024

Abstract excerpt

Animal models for retinal degeneration are essential for elucidating its pathogenesis and developing new therapeutic strategies in humans. N-methyl-N-nitrosourea (MNU) has been extensively used to construct a photoreceptor-specific degeneration model, which has served to unveil the molecular process of photoreceptor degeneration as well as the mechanisms regulating the protective responses of remaining cells....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Retinal Development and Disorders
Share to Retinal Diseases and Treatments
Share to Retinoids in leukemia and cellular processes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38167441
DOI: 10.1038/s41598-023-50485-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effects of different alkylating agents on photoreceptor degeneration and proliferative response of Müller gliaPMID 38167441Read ↗

Photoreceptor protection by mesenchymal stem cell transplantation identifies exosomal MiR-21 as a therapeutic for retinal degenerationSemantic proximity Read ↗

Melatonin As a Modulator of Degenerative and Regenerative Signaling Pathways in Injured Retinal Ganglion CellsSemantic proximity Read ↗

Genetic and epigenetic regulators of retinal Müller glial cell reprogrammingSemantic proximity Read ↗

Astragaloside A Protects Against Photoreceptor Degeneration in Part Through Suppressing Oxidative Stress and DNA Damage-Induced Necroptosis and Inflammation in the RetinaSemantic proximity Read ↗

Early postnatal Müller cell death leads to retinal but not optic nerve degeneration in NSE-Hu-Bcl-2 transgenic miceSemantic proximity Read ↗

Pax6-positive Müller glia cells express cell cycle markers but do not proliferate after photoreceptor injury in the mouse retina.Semantic proximity Read ↗

Wedelolactone Attenuates N-methyl-N-nitrosourea-Induced Retinal Neurodegeneration through Suppression of the AIM2/CASP11 PathwaySemantic proximity Read ↗

Characterization of retinal regeneration in adult zebrafish following multiple rounds of phototoxic lesionSemantic proximity Read ↗

Regulation of Stem Cell Properties of Müller Glia by JAK/STAT and MAPK Signaling in the Mammalian RetinaSemantic proximity Read ↗

Reprogramming of endogenous Müller cells into photoreceptor-like cells induced by small-molecule compounds in miceSemantic proximity Read ↗

Heterogeneity in quiescent Müller glia in the uninjured zebrafish retina drive differential responses following photoreceptor ablationSemantic proximity Read ↗

Heterogeneity in quiescent Müller glia in the uninjured zebrafish retina drive differential responses following photoreceptor ablationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.