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Harnessing Attenuation-Related Mutations of Viral Genomes: Development of a Serological Assay to Differentiate between Capripoxvirus-Infected and -Vaccinated Animals.

Viruses - 25 Nov 2023

Berguido Francisco J, Chibssa Tesfaye Rufael, Loitsch Angelika, Liu Yang, Krstevski Kiril, Djadjovski Igor, Tuppurainen Eeva, Petrović Tamaš, Vidanović Dejan, Caufour Philippe, Settypalli Tirumala Bharani K, Grünwald-Gruber Clemens, Grabherr Reingard, Diallo Adama, Cattoli Giovanni, Lamien Charles Euloge

Abstract excerpt

Sheeppox, goatpox, and lumpy skin disease caused by the sheeppox virus (SPPV), goatpox virus (GTPV), and lumpy skin disease virus (LSDV), respectively, are diseases that affect millions of ruminants and many low-income households in endemic countries, leading to great economic losses for the ruminant industry. The three viruses are members of the Capripoxvirus genus of the Poxviridae family. Live attenuated...

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Identifiers

PMID: 38140559
DOI: 10.3390/v15122318
PMCID: PMC10747038

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