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Bioinformatics-led discovery of liver-specific genes and macrophage infiltration in acute liver injury

7 Dec 2023

Abstract excerpt

Background: Acute liver injury (ALI) is an important global health concern, primarily caused by widespread hepatocyte cell death, coupled with a complex immune response and a lack of effective remedies. This study explores the underlying mechanisms, immune infiltration patterns, and potential targets for intervention and treatment ALI. Methods: The datasets of acetaminophen (APAP), carbon tetrachloride (CCl4),...

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PMID: 38130716
DOI: 10.3389/fimmu.2023.1287136

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