Article
Development and validation of clinical-radiomics analysis for preoperative prediction of IDH mutation status and WHO grade in diffuse gliomas: a consecutive L-[methyl-11C] methionine cohort study with two PET scanners.
European journal of nuclear medicine and molecular imaging - 1 Apr 2024
Zhou Weiyan, Wen Jianbo, Huang Qi, Zeng Yan, Zhou Zhirui, Zhu Yuhua, Chen Lei, Guan Yihui, Xie Fang, Zhuang Dongxiao, Hua Tao
Abstract excerpt
PURPOSE: Determination of isocitrate dehydrogenase (IDH) genotype is crucial in the stratification of diagnosis and prognostication in diffuse gliomas. We sought to build and validate radiomics models and clinical features incorporated nomogram for preoperative prediction of IDH mutation status and WHO grade of diffuse gliomas with L-[methyl-11C] methionine ([11C]MET) PET/CT imaging according to the 2016 WHO...
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