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Article

The miRNA variants MIR196A2 (rs11614913) and MIR423 (rs6505162) contribute to an increase in the risk of myocardial infarction.

Molecular genetics & genomic medicine - 1 Jan 2024

Uzair Muhammad, Haq Taqweem Ul, Ali Sajjad, Hussain Manzar, Jalil Fazal, Ali Yasir, Shah Aftab Ali

Abstract excerpt

INTRODUCTION: MicroRNAs (miRNAs) are small, single-stranded RNA molecules that negatively regulate gene expression and play a key role in the pathogenesis of human diseases. Recent studies have suggested that miRNAs contribute to cardiovascular diseases (CVDs). However, the association between single-nucleotide polymorphisms (SNPs) in miRNAs and myocardial infarction (MI) remains in infancy. AIM: The current...

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PMID: 38013659
DOI: 10.1002/mgg3.2323
PMCID: PMC10767615

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