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Skeletal Muscle Gene Expression Signatures of Obese High and Low Responders to Endurance Exercise Training

21 Nov 2023

Abstract excerpt

CONTEXT: Exercise training is known to improve glucose tolerance and reverse insulin resistance in people with obesity. However, some individuals fail to improve or even decline in their clinical traits following exercise intervention. OBJECTIVE: This study focused on gene expression and DNA methylation signatures in skeletal muscle of low (LRE) and high responders (RES) to 8 weeks of supervised endurance...

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PMID: 37988600
DOI: 10.1210/clinem/dgad677

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