Article
Understanding the contagiousness of Covid-19 strains: A geometric approach.
Journal of molecular graphics & modelling - 1 Jan 2024
Vottero Paola, Olivetti Elena Carlotta, D'Agostino Lucia Chiara, Di Grazia Luca, Vezzetti Enrico, Aminpour Maral, Tuszynski Jacek Adam, Marcolin Federica
Abstract excerpt
Protein-protein interaction occurs on surface patches with some degree of complementary geometric and chemical features. Building on this understanding, this study endeavors to characterize the spike protein of the SARS-CoV-2 virus at the morphological and geometrical levels in its Alpha, Delta, and Omicron variants. In particular, the affinity between different SARS-CoV-2 spike proteins and the ACE2 receptor...
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