Heart Failure, Female Sex, and Atrial Fibrillation Are the Main Drivers of Human Atrial Cardiomyopathy: Results From the CATCH ME Consortium.

doi:10.1161/JAHA.123.031220

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Article

Heart Failure, Female Sex, and Atrial Fibrillation Are the Main Drivers of Human Atrial Cardiomyopathy: Results From the CATCH ME Consortium.

Journal of the American Heart Association - 21 Nov 2023

Winters Joris, Isaacs Aaron, Zeemering Stef, Kawczynski Michal, Maesen Bart, Maessen Jos, Bidar Elham, Boukens Bas, Hermans Ben, van Hunnik Arne, Casadei Barbara, Fabritz Larissa, Chua Winnie, Sommerfeld Laura, Guasch Eduard, Mont Luis, Batlle Montserrat, Hatem Stephane, Kirchhof Paulus, Wakili Reza, Sinner Mortiz, Stoll Monica, Goette Andreas, Verheule Sander, Schotten Ulrich

Abstract excerpt

BACKGROUND: Atrial cardiomyopathy (atCM) is an emerging prognostic factor in cardiovascular disease. Fibrotic remodeling, cardiomyocyte hypertrophy, and capillary density are hallmarks of atCM. The contribution of etiological factors and atrial fibrillation (AF) to the development of differential atCM phenotypes has not been quantified. This study aimed to evaluate the association between histological features of...

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PMID: 37982389
DOI: 10.1161/JAHA.123.031220
PMCID: PMC10727294

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