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Article

Fibromodulin overexpression drives oral squamous cell carcinoma via activating downstream EGFR signaling

13 Oct 2023

Abstract excerpt

Accumulating evidence has shown that fibromodulin (FMOD) plays a pivotal role in tumorigenesis and metastasis. However, the biological function of FMOD in oral squamous cell carcinoma (OSCC) remains largely unclear to date. In this study, we confirmed that FMOD was overexpressed and showed a significant association with malignant progression and lymph node metastasis in OSCC. Depletion of FMOD inhibited OSCC...

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PMID: 37965134
DOI: 10.1016/j.isci.2023.108201

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