Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Does a detectable HCV RNA at the end of DAA therapy herald treatment failure?

Antiviral research - 1 Dec 2023

Zarębska-Michaluk Dorota, Flisiak Robert, Janczewska Ewa, Berak Hanna, Mazur Włodzimierz, Janocha-Litwin Justyna, Krygier Rafał, Dobracka Beata, Jaroszewicz Jerzy, Parfieniuk-Kowerda Anna, Dobrowolska Krystyna, Rzymski Piotr

Abstract excerpt

BACKGROUND & AIMS: The study aimed to assess the phenomenon of achieving sustained virologic response (SVR) in patients with detectable ribonucleic acid (RNA) of hepatitis C virus (HCV) at the end of treatment (ET) with direct-acting antivirals (DAA), find how this is affected by the type of regimen, and how patients experiencing this differed from non-responders with detectable HCV RNA at the ET. METHODS: The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antiviral Agents
Share to Drug Therapy, Combination

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hepacivirus

Share to Hepatitis C

Share to Hepatitis C, Chronic

Share to Sofosbuvir

Share to Treatment Failure

Source

Identifiers

PMID: 37944825
DOI: 10.1016/j.antiviral.2023.105742

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Does a detectable HCV RNA at the end of DAA therapy herald treatment failure?PMID 37944825Read ↗

Four weeks of off-treatment follow-up is sufficient to determine virologic responses at off-treatment week 12 in patients with hepatitis C virus infection receiving pangenotypic direct-acting antiviralsSemantic proximity Read ↗

Rescue Therapy after Failure of HCV Antiviral Treatment with Interferon-Free Regimens.Semantic proximity Read ↗

Implications of HCV RNA level at week 4 of direct antiviral treatments for hepatitis C.Semantic proximity Read ↗

Loss to follow-up of patients after antiviral treatment as an additional barrier to HCV eliminationSemantic proximity Read ↗

Positive predictive value of sustained virologic response 4 weeks posttreatment for achieving sustained virologic response 12 weeks posttreatment in patients receiving glecaprevir/pibrentasvir in Phase 2 and 3 clinical trials.Semantic proximity Read ↗

Longitudinal assessment of HCV core antigen kinetics to monitor therapeutic response in the age of DAAs.Semantic proximity Read ↗

Decompensated cirrhosis and liver transplantation negatively impact in DAA treatment response: Real-world experience from HCV-LALREAN cohort.Semantic proximity Read ↗

Sustained Virological Response After Early Discontinuation of Hepatitis C Treatment.Semantic proximity Read ↗

Concordance of SVR12, SVR24 and SVR durability in Taiwanese chronic hepatitis C patients with direct-acting antivirals.Semantic proximity Read ↗

On-treatment HCV RNA as a predictor of sustained virological response in HCV genotype 3-infected patients treated with daclatasvir and sofosbuvir.Semantic proximity Read ↗

Sustained Virologic Response at 24 Weeks after the End of Treatment Is a Better Predictor for Treatment Outcome in Real-World HCV-Infected Patients Treated by HCV NS3/4A Protease Inhibitors with Peginterferon plus Ribavirin.Semantic proximity Read ↗

Week 4 response predicts sustained virological response to all-oral direct-acting antiviral-based therapy in cirrhotic patients with hepatitis C virus genotype 3 infection.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.