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Article

Concordance of SVR12, SVR24 and SVR durability in Taiwanese chronic hepatitis C patients with direct-acting antivirals.

PloS one - 1 Jan 2021

Lin Chuan-Pin, Liang Po-Cheng, Huang Ching-I, Yeh Ming-Lun, Hsu Po-Yao, Hsu Cheng-Ting, Wei Yu-Ju, Liu Ta-Wei, Hsieh Ming-Yen, Hou Nai-Jen, Jang Tyng-Yuang, Lin Yi-Hung, Wang Chih-Wen, Lin Zu-Yau, Chen Shinn-Cherng, Huang Chung-Feng, Huang Jee-Fu, Dai Chia-Yen, Chuang Wan-Long, Yu Ming-Lung

Abstract excerpt

BACKGROUND/AIMS: Undetectable HCV RNA 12 weeks after the end of treatment (SVR12) has been the valid efficacy endpoint in the era of direct-acting antivirals (DAAs). Its concordance with SVR4 and SVR24 and long-term durability is unknown in Taiwanese chronic hepatitis C (CHC) patients. METHODS: A total of 1080 CHC patients who received all-oral DAAs and an achieved end-of-treatment virological response (EOTVR),...

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Identifiers

PMID: 33539408
DOI: 10.1371/journal.pone.0245479
PMCID: PMC7861540

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