Article
Persistent ciprofloxacin exposure induced the transformation of Klebsiella pneumoniae small colony variant into mucous phenotype.
Frontiers in cellular and infection microbiology - 1 Jan 2023
Zou Hua, Li Qian, Su Yan, Zhang Lei, Zhang Xinyuan, Li Chunli
Abstract excerpt
Introduction: Small colony variant (SCV) is a bacterial phenotype closely related to persistent and recurrent infections. SCVs are mutations that occur within bacterial populations, resulting in a change in bacterial morphology and the formation of small colonies. This morphological change may enhance bacterial resistance to antibiotics and contribute to persistent and recurrent infections. Methods: We isolated...
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