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β-Carbolines norharman and harman change neurobehavior causing neurological damage in Caenorhabditis elegans

1 Jan 2023

Abstract excerpt

). The survival rate and indicators of ethology (locomotor behaviors, foraging behavior, and chemotaxis ability) were assessed. The antioxidant system and the contents of neurotransmitters, as well as the activity of acetylcholinesterase (AChE), were evaluated. Additionally, the RNA-seq screening of differentially expressed genes (DEGs) revealed the potential molecular mechanisms of norharman- and harman-induced...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37927231
DOI: 10.1039/d3fo03732k

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