Article
Histo-Molecular Factors of Response to Combined Chemotherapy and Immunotherapy in Non-Small Cell Lung Cancers.
Targeted oncology - 1 Nov 2023
Marchal Marine, Leroy Vincent, Behal Hélène, Dansin Eric, Paris Nicolas, Bordier Soraya, Humez Sarah, Escande Fabienne, Gauvain Clément, Cortot Alexis B
Abstract excerpt
BACKGROUND: Chemo-immunotherapy (CIT) is the standard of care for advanced non-small cell lung cancer (NSCLC), but the impact of routinely available histo-molecular biomarkers on its efficacy has not yet been fully assessed. OBJECTIVE: The purpose of this multicenter study was to evaluate the clinical activity of CIT according to oncogenic drivers, STK11 and TP53 mutations, and MET overexpression. PATIENTS AND...
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